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Introduction＆R．LEE CLARK1

STRUCTURE OF VIRUSES5

A Comparative Study of the Structures of a Variety of Bacteriophage Particles with Some Observations on the Mechanism of Nucleic Acid Injection＆DESMOND KAY7

Structure and Assembly of Regular Virus Particles＆D．L．D．CASPAR and A．KLUG27

Electron Microscope Studies on the Structure and Symmetry of Virus Particles＆R．W．HORNE40

Icosahedral Viruses—A Geometric Approach to Their Maturation＆HEATHER DONALD MAYOR63

Morphology of the RNA Phage FH5＆J．HUPPERT，ANTOINETTE RYTER，and JEANNE FOUACE68

The Arthropod Viruses＆KENNETH M．SMITH72

Studies on the Structure of the Mammary Tumor-Inducing Virus(Bittner)and of Leukemia Virus(Gross)＆L．DMOCHOWSKI，C．E．GREY，F．PADGETT，and J．A．SYKES85

Structure and Genetic Properties of Bacterial Viruses＆THOMAS F．ANDERSON122

Virus Particles of Mouse Lymphomas and Mammary Carcinoma＆R．KINOSITA and T．KAKEFUDA141

REPLICATION OF VIRUSES：BIOCHEMISTRY OF VIRUS-INFECTED CELLS149

Influence of Phages on the Synthesis of Host Enzymes of Bacteria＆MICHAEL B．YARMOLINSKY151

The Functions of the RNA of Bacteriophage f2＆NORTON D．ZINDER173

Substances Produced During Replication of Plant Viruses＆ROY MARKHAM180

Biosynthesis of Viral Ribonucleic Acids＆M．HOMMA，A．V．RAKE，W．PARANCHYCH，D．B．ELLIS，and A．F．GRAHAM191

The Programing of Herpes Virus Multiplication in Mammalian Cells＆BERNARD ROIZMAN205

Studies of Replication and Properties of the Bittner Virus＆DAN H．MOORE and MICHAEL J．LYONS224

VIRAL NUCLEIC ACID：PROPERTIES AND MODE OF REPLICATION243

Viral Nucleic Acid：Properties and Mode of Replication．Introduction＆W．M．STANLEY245

Replication of the Nucleic Acids of the Bacterial Viruses＆ROBERT L．SINSHEIMER246

Biosynthesis of Infectious Ribonucleic Acid of Tobacco Mosaic Virus by Extracts of Healthy Plants＆GEORGE W．COCHRAN252

Properties of the DNA of Polyoma Virus＆RENATO DULBECCO271

Early Events in the Reproduction Cycle of Animal Viruses＆P．HAUSEN，H．HAUSEN，R．ROTT，C．SCHOLTISSEK，and W．SCH？FER282

Early Changes Following Virus Infection：Thymidine Kinase Induction in Cells Infected with Vaccinia and Herpes Simplex Viruses＆SAUL KIT296

Changes in RNA and Protein Synthesis in Mammalian Cells Infected with a Virulent Virus＆RICHARD M．FRANKLIN and DAVID BALTIMORE310

AVIAN VIRUSES AND NEOPLASIA327

Avian Viruses and Neoplasia：Introduction＆W．R．BRYAN329

Biological and Structural Properties of Rous Sarcoma Viruses＆R．J．C．HARRIS331

Studies on the Biological，Biochemical，and Biophysical Properties of Avian Tumor Viruses＆J．W．BEARD，R．A．BONAR，URSULA HEINE，GUY DE THé，and DOROTHY BEARD344

The Infection of Chicken Fibroblast Cultures by Avian Myeloblastosis Virus＆PETER K．VOGT374

Induction of Differentiation in Certain Target Cells by Avian Myeloblastosis Virus：An In Vitro Study＆M．A．BALUDA，I．E．GOETZ，and S．OHNO387

BERTNER FOUNDATION LECTURE401

Properties of a Virus Isolated from Leukemic Mice，Inducing Various Forms of Leukemia and Lymphomas in Mice and Rats＆LUDWIK GROSS403

VIRUSES AND INTERFERON427

Viruses and Interferon：Introduction＆W．HENLE429

Interference and Cell Division＆KURT PAUCKER430

The Effect of Interferon on the Synthesis of Viral Nucleic Acid＆ROYCE Z．LOCKART，JR．，and T．SREEVALSAN447

Interference and Interferon in Relation to Tumor Viruses and Tumor Cells＆A．C．ALLISON462

BIOLOGICAL ASPECTS OF TUMOR INDUCTION BY VIRUSES485

The Interaction of Polyoma Virus with Hamster Fibroblasts＆MICHAEL STOKER487

The Role of the Mammary Tumor Virus in Mouse Mammary Noduligenesis and Tumorigenesis＆K．B．DEOME498

Significance of the Absence of Infectious Virus in Virus-Induced Tumors＆H．RUBIN and H．HANAFUSA508

INTERRELATIONSHIP OF VIRUSES：INTRACELLULAR AND EXTRACELLULAR FACTORS IN NEOPLASIA527

The Possible Role of a＂Transmissible Factor＂in Leukemia Induction by Radiation Plus Urethan＆I．BERENBLUM529

The Combined Action of Viruses and Other Carcinogens＆M．H．SALAMAN，K．E．K．ROWSON，F．J．C．ROE，J．K．BALL，J．J．HARVEY，and G．DE BENEDICTIS544

Studies on the Oncogenicity of Human Adenovirus＆JOHN J．TRENTIN，YOSHIRO YABE，and GRANT TAYLOR559

Observations on a Specific Adenovirus 12 Antigen in Virus-Free Adenovirus Tumor Transplants＆R．J．HUEBNER，W．P．ROWE，and L．D．BERMAN564

Lymphoma in ICR Mice Treated with 4-Nitroquinoline N-Oxide (4-NQO)＆R．KINOSITA and T．TANAKA571

＂Newer＂and＂Older＂Viruses in Mammalian Malignancy＆MAURICE R．HILLEMAN580

A Children＇s Cancer Dependent on Environment＆DENIS BURKITT615

The Role of Viruses in Relation to Cancer in Animals and Man＆FRANK L．HORSFALL，JR．630

Index643